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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK7
All Species:
10
Human Site:
T316
Identified Species:
14.67
UniProt:
P50613
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50613
NP_001790.1
346
39038
T316
R
P
N
C
P
V
E
T
L
K
E
Q
S
N
P
Chimpanzee
Pan troglodytes
XP_518193
305
34323
S280
V
E
T
L
K
E
Q
S
N
P
A
L
A
I
K
Rhesus Macaque
Macaca mulatta
XP_001092242
346
39008
T316
R
P
N
C
P
V
E
T
L
K
E
Q
S
N
P
Dog
Lupus familis
XP_850424
354
39795
T324
R
P
N
C
P
L
E
T
L
K
E
Q
S
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q03147
346
38950
A316
R
P
N
C
P
V
E
A
L
K
E
P
A
N
P
Rat
Rattus norvegicus
P51952
329
37122
V306
L
P
R
P
N
C
P
V
E
A
L
K
E
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506541
324
36280
A294
R
P
N
C
P
A
E
A
L
K
E
S
Q
H
P
Chicken
Gallus gallus
P13863
303
34670
G278
D
P
A
K
R
I
S
G
K
M
A
L
N
H
P
Frog
Xenopus laevis
P20911
352
39672
A322
R
P
N
C
S
I
E
A
L
K
E
Q
Q
N
L
Zebra Danio
Brachydanio rerio
A8WIP6
344
39006
H309
I
P
Q
R
G
G
K
H
S
R
Q
R
M
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511044
353
39655
A316
M
P
S
A
I
L
A
A
K
E
G
A
N
P
Q
Honey Bee
Apis mellifera
XP_395800
321
36188
Q295
L
P
T
S
V
K
R
Q
P
E
E
K
P
S
L
Nematode Worm
Caenorhab. elegans
P34556
332
38277
L307
R
L
N
A
K
K
A
L
V
H
P
Y
F
D
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
E271
L
S
K
M
L
R
Y
E
P
S
K
R
I
T
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT0
391
44511
G313
K
P
V
P
K
Q
D
G
K
S
S
Y
G
K
H
Baker's Yeast
Sacchar. cerevisiae
P06242
306
35228
V282
P
Q
K
R
W
T
A
V
Q
C
L
E
S
D
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
99.7
92.6
N.A.
95
91
N.A.
87.5
39.8
85.2
42.2
N.A.
65.7
63.8
39.3
N.A.
Protein Similarity:
100
88.1
99.7
95.4
N.A.
96.8
92.4
N.A.
88.7
56.3
90.3
59.5
N.A.
78.4
75.1
57.5
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
80
6.6
N.A.
66.6
13.3
66.6
13.3
N.A.
6.6
13.3
13.3
N.A.
P-Site Similarity:
100
20
100
100
N.A.
86.6
13.3
N.A.
73.3
33.3
73.3
40
N.A.
33.3
33.3
26.6
N.A.
Percent
Protein Identity:
N.A.
39.3
N.A.
49.1
41
N.A.
Protein Similarity:
N.A.
57.8
N.A.
65.2
60.6
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
13
0
7
19
25
0
7
13
7
13
0
7
% A
% Cys:
0
0
0
38
0
7
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
7
0
0
0
0
0
0
13
0
% D
% Glu:
0
7
0
0
0
7
38
7
7
13
44
7
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
7
7
0
13
0
0
7
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
7
0
0
0
13
7
% H
% Ile:
7
0
0
0
7
13
0
0
0
0
0
0
7
7
0
% I
% Lys:
7
0
13
7
19
13
7
0
19
38
7
13
0
7
7
% K
% Leu:
19
7
0
7
7
13
0
7
38
0
13
13
0
0
13
% L
% Met:
7
0
0
7
0
0
0
0
0
7
0
0
7
0
0
% M
% Asn:
0
0
44
0
7
0
0
0
7
0
0
0
13
32
7
% N
% Pro:
7
75
0
13
32
0
7
0
13
7
7
7
7
7
44
% P
% Gln:
0
7
7
0
0
7
7
7
7
0
7
25
13
13
7
% Q
% Arg:
44
0
7
13
7
7
7
0
0
7
0
13
0
0
0
% R
% Ser:
0
7
7
7
7
0
7
7
7
13
7
7
25
7
7
% S
% Thr:
0
0
13
0
0
7
0
19
0
0
0
0
0
7
0
% T
% Val:
7
0
7
0
7
19
0
13
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
13
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _